In Vitro Antimicrobial Activity and Phytochemical Screening of Jatropha curcas Seed Extract.

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dc.contributor.authorAransiola, S.A.
dc.date.accessioned2025-02-21T11:09:26Z
dc.date.available2025-02-21T11:09:26Z
dc.date.issued2011
dc.description.abstractThe antimicrobial effects of the methanol, ethyl acetate and hexane extracts of J.curcas seed at concentration ranging from 50-200mg/ml were tested against some pathogenic organisms using agar diffusion method; the extracts exhibited antimicrobial activities with the zones of inhibition ranging from 10-25, 8-23, 10-20 and 12-21(mg/ml) for Staphylococcus aureus, Escherichia coli, Salmonella typhi and Candida albican, respectively. The Minimum Inhibitory Concentration (MIC) which ranges from 3.13-12.5mg/ml was determined using the broth dilution method; the Minimum Bactericidal Concentration (MBC) ranges from 25-2.25mg/ml. The phytochemical analysis revealed the presence of alkaloid, glycosides,flavonoid and carbohydrate. The ability of the crude seed extracts of J.curcas to inhibit bacteria and fungi is an indication of its broad spectrum antimicrobial potential which may be employed in the management of microbial infections. It is necessary to determine the active dosage level so as to be able to formulate it into a pharmaceutical dosage for use in chemotherapy.
dc.identifier.citationDaniyan, S.Y., Abalaka, M.E., Elemba, O.M. and Aransiola, S.A., 2011. In vitro antimicrobial activity and phytochemical screening of Jatropha curcas seed extract. International Research Journal of Pharmacy, 2(7), pp.60-64.
dc.identifier.urihttp://ajphs.com/archdet.php?j=36
dc.identifier.urihttps://repository.uniabuja.edu.ng/handle/123456789/728
dc.language.isoen
dc.publisherInternational Research Journal of Pharmacy
dc.subjectAntimicrobial activities
dc.subjectMicrobial infections
dc.subjectInhibition
dc.titleIn Vitro Antimicrobial Activity and Phytochemical Screening of Jatropha curcas Seed Extract.
dc.typeArticle
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