Welcome to University of Abuja institutional repository for research material including: journal articles, conference papers, practice research, video, audio, art works and exhibitions, books and book chapters, doctoral theses and datasets. The repository provides full text access where permitted, and full citation details where restrictions apply. Please contact the Research Support Team (repository@uniabuja.edu.ng) with any related queries.

Recent Submissions

Item
In Vitro Antimicrobial Activity and Phytochemical Screening of Jatropha curcas Seed Extract.
(International Research Journal of Pharmacy, 2011) Aransiola, S.A.
The antimicrobial effects of the methanol, ethyl acetate and hexane extracts of J.curcas seed at concentration ranging from 50-200mg/ml were tested against some pathogenic organisms using agar diffusion method; the extracts exhibited antimicrobial activities with the zones of inhibition ranging from 10-25, 8-23, 10-20 and 12-21(mg/ml) for Staphylococcus aureus, Escherichia coli, Salmonella typhi and Candida albican, respectively. The Minimum Inhibitory Concentration (MIC) which ranges from 3.13-12.5mg/ml was determined using the broth dilution method; the Minimum Bactericidal Concentration (MBC) ranges from 25-2.25mg/ml. The phytochemical analysis revealed the presence of alkaloid, glycosides,flavonoid and carbohydrate. The ability of the crude seed extracts of J.curcas to inhibit bacteria and fungi is an indication of its broad spectrum antimicrobial potential which may be employed in the management of microbial infections. It is necessary to determine the active dosage level so as to be able to formulate it into a pharmaceutical dosage for use in chemotherapy.
Item
Production of laccase by Bacillus subtilis and Aspergillus niger for treatment of textile effluent
(Sustainable Chemistry for the Environment, 2025) Aransiola, S.A.
The improper disposal of textile effluents without effective treatment has adverse environmental, social, economic, and health impacts and as such, it is vital to find innovative technological solutions to reduce the negative consequences of textile effluents. Laccases are versatile multicopper enzymes found in plants, fungi and other microorganisms with wide applications especially in the textile and paper industry. This study examined the production of laccase from Bacillus subtilis and Aspergillus niger to remediate textile effluent. Both organisms were identified by molecular method and plate test method was used to evaluate laccase production by the two organisms. Rice bran emerged as the substrate of choice for laccase production. At optimum temperature (30°C), the highest laccase produced was 0.522 U/mL and 0.642 U/mL at 35°C for B. subtilis and A. niger respectively. The optimum pH level of 5 and 6 produced the highest laccase yield of 0.583 U/mL and 0.684 U/mL respectively. Significant improvements of laccases from B. subtilis and A. niger were observed on physicochemical analysis of TDS, pH, electrical conductivity, TSS, temperature and DO in treating textile effluent. Notably, these enzymes exhibited remarkable efficacy reduction in BOD (38 %), COD (14 %), and nitrate (23 %) levels in the effluent. The study underscores the efficacy of laccases from the microorganisms in treating textile effluent, with concentrations ranging from 10 to 30 U/mL proving effective. However, laccase produced from B. subtilis showed more remediation potential in textile effluent treatment compared to the one produced by A. niger
Item
Roles of Marine Microbial Products to the Nigeria Economy.
(Springer Cham, 2024) Aransiola, S.A.
Metabolites and/or products originating from living things, including microbes, plants, and animals, are referred to as natural products. For thousands of years, people have used and consumed natural goods in various forms all across the world. Natural products derived from marine microbial sources have gained a lot of attention lately because of developments in X-ray crystallography, spectroscopy, deep-sea exploration technology, and other separation techniques. It is believed that the harsh conditions found in the sea, which include high or low temperatures, high pressure, low pH, and high salt concentrations, give marine microbial products their distinct physiological characteristics and unusual chemical structures. Because symbiotic microbes that produce natural products coexist with macroorganisms such as sponges and corals, it is also possible to extract marine natural products of microbial origins from them. Bacteria, fungi, viruses, microalgae, marine micro-animals, and symbiotic microorganisms are some of the major categories of marine microorganisms. More than 30,000 marine microbial products have been found since the first ones were isolated in the 1950s. Nigeria has a lot of potential for extracting lucrative marine microbial products because of its long coastline and big surface area. Products made from marine microorganisms are widely employed in the food and beverage, agricultural, cosmetic, and pharmaceutical industries. The Nigerian economy and its businesses stand to gain greatly from these broad use cases. However, to fully capitalize on these advantages, a thorough investigation of Nigeria’s maritime habitats should be carried out in conjunction with companies to find and market marine microbial goods.
Item
Treatment of Pharmaceutical Effluent by Saccharomyces cerevisiae and Torulaspora delbrueckii Isolated from Spoilt Water Melon
(Research Journal of Environmental Toxicology, 2015) Aransiola, S.A.
A study was designed to assess the efficacy of yeast isolated from spoilt water melon in the biological treatment of pharmaceutical effluent. There were two yeast species identified as Saccharomyces cerevisiae and Torulaspora delbrueckii. Each of the yeast was inoculated into the effluent and incubated for 15 days. Saccharomyces cerevisiae shows the highest percentage reduction of 52.5%, 52.5% and 58.7% for BOD, COD and nitrate respectively of the pharmaceutical effluent and closely followed by the consortium which has 44.5%, 44.5% and 72.0% for BOD, COD and nitrate reduction, respectively. The least percentage reduction was displayed by Torulaspora delbrueckii with 38.3%, 38.3% and 79.7%. The study revealed that Saccharomyces cerevisiae isolated from spoilt water melon could be used in the biological treatment of pharmaceutical effluent.
Item
Deregulation of Nigeria’s Natural Resources Sector as a Catalyst for National Development
(KIU Journal of Social Sciences, 2018) Kontagora, A.M
For over 40 years Nigeria's economy was driven by petroleum. During this period, her influence in Africa soared. It peaked in the 1970s and 80s, so much so that she spent oil money on the decolonization of certain countries in Africa. Natural Resource in Nigeria is owned by the people, but administered for the overall benefit of Nigerians by government. This precious natural gift lost its pride of place when the worth of petroleum dipped in the international market. Prior to this economic decline, Nigeria adopted a near socialist system by operating a subsidy regime. Because what belongs to government belongs to no specific person, Nigerian past leaders became profligate. A public property is nobody's property and can be misused and mismanaged. So, Natural Resources is a gift from God to be used to develop a given area or country for the betterment of the people. Natural Resources can be better harnessed by private enterprise. Thus, deregulation in the least, or outright privatization is the best option in maximizing natural resources.