Faculty of Basic Medical Sciences

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    Effects of exercise on PR intervals, QRS durations and QTC intervals in male and female students of University of Abuja.
    (JPMA-Journal of the Pakistan Medical Association, 2012-03) Ogedengbe, John Onimisi; Adelaiye, Alexander Babatunde
    A study was conducted to determine the effect of exercise on Electrocardiogram (ECG) variables in students of University of Abuja, and gender variation of these variables was compared. Forty medical students were considered (22 males and 18 females), ages 18-30 years. The volunteers were subjected to exercise stress test by using bicycle ergometer. They exercised till exhaustion or attainment of 85% Heart Rate Maximum (HRmax) (Modified McArdle Protocol). ECGwas recorded pre and post-exercise. QTcintervals pre and post-exercise were 386.55 +/- 4.4ms and 415.82 +/- 4.89ms (range: 346 - 468ms) in males and 399.39 +/- 4.81ms and 409.11 +/- 4.44ms (range: 367 - 446ms) in females respectively. QTC was significantly raised post-exercise in male subjects. PR interval pre and postexercise were 153 +/- 5.09ms and 154.75 +/- 3.35ms (range: 116 - 206ms) in males and 160.44 +/- 6.5ms and 153.33 +/- 4.53ms (range: 116 - 243ms) in females respectively. QRS duration pre and post-exercise were found to be 90.86 +/- 0.97ms and 94.09 +/- 2.09ms (range: 83 - 122ms) in males and 87.44 +/- 1.36ms and 88.89 +/- 2.06ms (range: 80 - 113ms) in females respectively.
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    Effects of exercise on PR intervals, QRS durations and QTC intervals in male and female students of University of Abuja.
    (2012-03) Ogedengbe, John Onimisi; Adelaiye, Alexander Babatunde
    A study was conducted to determine the effect of exercise on Electrocardiogram (ECG) variables in students of University of Abuja, and gender variation of these variables was compared. Forty medical students were considered (22 males and 18 females), ages 18-30 years. The volunteers were subjected to exercise stress test by using bicycle ergometer. They exercised till exhaustion or attainment of 85% Heart Rate Maximum (HRmax) (Modified McArdle Protocol). ECGwas recorded pre and post-exercise. QTcintervals pre and post-exercise were 386.55 +/- 4.4ms and 415.82 +/- 4.89ms (range: 346 - 468ms) in males and 399.39 +/- 4.81ms and 409.11 +/- 4.44ms (range: 367 - 446ms) in females respectively. QTC was significantly raised post-exercise in male subjects. PR interval pre and postexercise were 153 +/- 5.09ms and 154.75 +/- 3.35ms (range: 116 - 206ms) in males and 160.44 +/- 6.5ms and 153.33 +/- 4.53ms (range: 116 - 243ms) in females respectively. QRS duration pre and post-exercise were found to be 90.86 +/- 0.97ms and 94.09 +/- 2.09ms (range: 83 - 122ms) in males and 87.44 +/- 1.36ms and 88.89 +/- 2.06ms (range: 80 - 113ms) in females respectively.
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    Heart Rate Variability in Healthy Young Adult Nigerians.
    (West African Journal of Medicine, 2024-06-28) Chori, B S; Adamu, D B; Onaadepo, O; Ogedengbe, J O; Odili, A N
    Objective: Heart rate variability (HRV) is a reliable, non-invasive indicator of autonomic balance. Its application in research and clinical medicine is hindered by the lack of consensus on normal values. This study sought to bridge this gap by providing normative values for short-term HRV measures in apparently healthy young adults. Methods: A descriptive cross-sectional study was carried out to determine short-term HRV measures using a 5-minute ECG recording among 840 healthy young adult Nigerians. Results: A total of 840 subjects between the ages of 15 - 40 years participated in the study, the majority of whom were women (56%). Mean (±SD) RR (ms), SDNN (ms), RMSSD (ms), LF (ms2), HF (ms2), LF (nu), HF (nu), and LF/HF were 831 (±138), 48 (±35), 57 (±49), 949 (±2598), 1802(±5135), 41 (±19), 58.90 (±19), and 1.42 (±4.6) respectively. Male participants had significantly higher mean RR (890.8 v 782.0, p<0.001), SDNN (52.4 v 43.8, p<0.005), RMSSD (63.6 v 50.9, p<0.005), LF (1218.5 v 731.8, p<0.001) and HF (2260.5 v 1429.5, p=0.002) than the female participants. No significant differences were found across age groups. Conclusion: Short-term resting HRV shows gender differences and higher vagally-mediated components among healthy young adults of native African descent. Interpretation of HRV parameters should take into account the age, gender, context, spectral analysis method, and duration of recording, among other factors.