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Item Effect of Saccharomyces cerevisiae on the Survival rate and Growth performance of Clarias gariepinus (Burchell, 1822)(Production Agriculture and Technology (PAT), 2024) Sadiq, Hauwa OhuneneThis study evaluated the efficacy of including Saccharomyces cerevisiae, Brewer’s yeast in the diet of Clarias gariepinus. Two hundred and twenty-five C. gariepinus sourced from Fisheries and Aquaculture Research Farm, Federal University Wukari, were used for the study. The fish were conditioned for 14 days, distributed into the experimental tanks consisting of 45 fish per treatment in three replicates in a completely randomised design model and were fed for 84 days. Five experimental diets were formulated with brewer’s yeast replacing fishmeal at 0% 25%, 50%, 75%, and 100% inclusion levels. The fish were fed 5% of their body weight twice daily. Growth parameters such as mean weight gain, specific growth rate, and survival rate were evaluated. The water quality parameters were monitored and recorded throughout the period of experiment. The results showed significant (p<0.05) differences on the feed intake (911.67g/day – 1120.33g/day), weight gain (401.7g – 459.0g), and specific growth rate (0.80g/day - 0.88g/day) of C. gariepinus. This apparently suggested that S. cerevisiae is a potential economical and nutritious feed ingredient for fish. Based on this finding, it was concluded that Saccharomyces cerevisiae can be included in fish diet up to 75% without impacting negatively on the growth performance of Clarias gariepinus.