Welcome to University of Abuja institutional repository for research material including: journal articles, conference papers, practice research, video, audio, art works and exhibitions, books and book chapters, doctoral theses and datasets. The repository provides full text access where permitted, and full citation details where restrictions apply. Please contact the Research Support Team (repository@uniabuja.edu.ng) with any related queries.

Recent Submissions

Item
Effects of exercise on PR intervals, QRS durations and QTC intervals in male and female students of University of Abuja.
(2012-03) Ogedengbe, John Onimisi; Adelaiye, Alexander Babatunde
A study was conducted to determine the effect of exercise on Electrocardiogram (ECG) variables in students of University of Abuja, and gender variation of these variables was compared. Forty medical students were considered (22 males and 18 females), ages 18-30 years. The volunteers were subjected to exercise stress test by using bicycle ergometer. They exercised till exhaustion or attainment of 85% Heart Rate Maximum (HRmax) (Modified McArdle Protocol). ECGwas recorded pre and post-exercise. QTcintervals pre and post-exercise were 386.55 +/- 4.4ms and 415.82 +/- 4.89ms (range: 346 - 468ms) in males and 399.39 +/- 4.81ms and 409.11 +/- 4.44ms (range: 367 - 446ms) in females respectively. QTC was significantly raised post-exercise in male subjects. PR interval pre and postexercise were 153 +/- 5.09ms and 154.75 +/- 3.35ms (range: 116 - 206ms) in males and 160.44 +/- 6.5ms and 153.33 +/- 4.53ms (range: 116 - 243ms) in females respectively. QRS duration pre and post-exercise were found to be 90.86 +/- 0.97ms and 94.09 +/- 2.09ms (range: 83 - 122ms) in males and 87.44 +/- 1.36ms and 88.89 +/- 2.06ms (range: 80 - 113ms) in females respectively.
Item
Heart Rate Variability in Healthy Young Adult Nigerians.
(West African Journal of Medicine, 2024-06-28) Chori, B S; Adamu, D B; Onaadepo, O; Ogedengbe, J O; Odili, A N
Objective: Heart rate variability (HRV) is a reliable, non-invasive indicator of autonomic balance. Its application in research and clinical medicine is hindered by the lack of consensus on normal values. This study sought to bridge this gap by providing normative values for short-term HRV measures in apparently healthy young adults. Methods: A descriptive cross-sectional study was carried out to determine short-term HRV measures using a 5-minute ECG recording among 840 healthy young adult Nigerians. Results: A total of 840 subjects between the ages of 15 - 40 years participated in the study, the majority of whom were women (56%). Mean (±SD) RR (ms), SDNN (ms), RMSSD (ms), LF (ms2), HF (ms2), LF (nu), HF (nu), and LF/HF were 831 (±138), 48 (±35), 57 (±49), 949 (±2598), 1802(±5135), 41 (±19), 58.90 (±19), and 1.42 (±4.6) respectively. Male participants had significantly higher mean RR (890.8 v 782.0, p<0.001), SDNN (52.4 v 43.8, p<0.005), RMSSD (63.6 v 50.9, p<0.005), LF (1218.5 v 731.8, p<0.001) and HF (2260.5 v 1429.5, p=0.002) than the female participants. No significant differences were found across age groups. Conclusion: Short-term resting HRV shows gender differences and higher vagally-mediated components among healthy young adults of native African descent. Interpretation of HRV parameters should take into account the age, gender, context, spectral analysis method, and duration of recording, among other factors.
Item
Fostering Critical Thinking and Global Awareness through Project-Based Learning in the 21st Century Classroom
(AFRICA DEVELOPMENT AND RESOURCES RESEARCH INSTITUTE, 2024-12-31) Nkopuruk, Imikan Nseobong
This study investigated the effectof Project -Based Learning (PBL) in promoting the growth of critical thinking and global awareness in the 21st -century classroom. Fueled by the backdrop of growing societal complexities and globalization, the research made a strong case for preparing students with some basic competencies beyond traditional academic knowledge. A quasi experimental design was used in which pre and post assessments of improvements in critical thinking abilities and global awareness were assessed in a sample of 100 students. The results showed that students who had been exposed to PBL have much better critical thinking skills and global competencies as compared to students who used the conventional instructional methods. We found PBL encouraged active learning and collaboration, and students demonstrated engagement toward real world issues that will prepare them to face complex global challenges. In addition, the research offered the best practices for integrating PBL into educational curricula. This contributes to the continuing discussion of alternative pedagogical methods that ameliorate the faults of typical education and, in doing so, better train students for success in an interconnected world.
Item
Microbial Biotechnology for Bioenergy
(Elsevier, 2024) Aransiola, Sesan Abiodun
Item
Exploring the Potential of Fungi in the Bioremediation of Pharmaceutically Active Compounds. Front. Microbiol. Sec. Microbiotechnology
(Front. Microbiol, 2023) Aransiola, Sesan Abiodun
The ability of fungal species to produce a wide range of enzymes and metabolites, which act synergistically, makes them valuable tools in bioremediation, especially in the removal of pharmaceutically active compounds (PhACs) from contaminated environments. PhACs are compounds that have been specifically designed to treat or alter animal physiological conditions and they include antibiotics, analgesics, hormones, and steroids. Their detrimental effects on all life forms have become a source of public outcry due their persistent nature and their uncontrolled discharge into various wastewater effluents, hospital effluents, and surface waters. Studies have however shown that fungi have the necessary metabolic machinery to degrade PhACs in complex environments, such as soil and water, in addition they can be utilized in bioreactor systems to remove PhACs. In this regard, this review highlights fungal species with immense potential in the biodegradation of PhACs, their enzymatic arsenal as well as the probable mechanism of biodegradation. The challenges encumbering the real-time application of this promising bioremediative approach are also highlighted, as well as the areas of improvement and future perspective. In all, this paper points researchers to the fact that fungal bioremediation is a promising strategy for addressing the growing issue of pharmaceutical contamination in the environment and can help to mitigate the negative impacts on ecosystems and human health.